Preliminary results of a first-in-human trial for a new CAR T-based treatment targeting two different sites on glioblastoma tumors result in dramatic, but transient, reductions in tumor size.

HMS News article on new research from Khalid Shah and colleagues, first author Kok-Siong Chen, on the development of a new cell therapy approach engineered to eliminate established tumors and to train the immune system to prevent cancer recurrence.

Harvard Gazette article on new research from Rakesh K. Jain and colleagues, co-first authors Zohreh Amoozgar, Jonas Kloepper, and Jun Ren, retraining tumor-promoting immune cells to fight most aggressive type of brain cancer.

This paper explores what NK cells do in response to nerve injury and how understanding that could lead to better treatments for pain.

HMS News article, on new research from the team of PierPaolo Peruzzi, E. Antonio Chiocca, and colleagues (first author Vivek Bhaskaran), showing how certain microRNAs can weaken brain cancer cells in advance of standard therapy in preclinical models.