ANNOUNCEMENTS
Call for Proposals – 2025 Bipolar Disorder Seed Grants
We are pleased to announce a new call for proposals for the HBI Bipolar Disorder Seed Grant Program, intended to support research relevant to the basic understanding and treatment of this disorder.
Applicants must be tenured or tenure-track faculty members at the assistant professor level or higher at Harvard University and its affiliated hospitals. Grants are for $200K total ($100K/year for two years).
Please click here for more information about the program and to access the complete RFA and LOI submission requirements.
LOIs are due Wed February 19th.
Questions can be sent to Parizad Bilimoria at HBI_Grants@harvard.edu.
Community Stories
The SKA2 Effect: Linking Stress and Bipolar Disorder
Jakob Hartmann and Kerry Ressler share new work uncovering how SKA2, a protein regulating stress-related signaling, interacts with the glucocorticoid receptor to maintain balance in the brain’s stress response. By highlighting altered SKA2 expression in bipolar disorder, this work offers new insights into the molecular underpinnings of stress-related psychiatric conditions and potential pathways for therapeutic intervention.
Jakob Hartmann and Kerry Ressler share new work uncovering how SKA2, a protein regulating stress-related signaling, interacts with the glucocorticoid receptor to maintain balance in the brain’s stress response. By highlighting altered SKA2 expression in bipolar disorder, this work offers new insights into the molecular underpinnings of stress-related psychiatric conditions and potential pathways for therapeutic intervention.
Double Agents: How Glial Tumors Take On Interneuronal Identities
How do pediatric brain tumors mimic normal brain development, and how can this be leveraged for therapies? Ilon Liu, Mariella Filbin and colleagues find that a specific brain tumor type resembles GABAergic interneuron development, and with this knowledge they identify novel targets against this lethal tumor.
How do pediatric brain tumors mimic normal brain development, and how can this be leveraged for therapies? Ilon Liu, Mariella Filbin and colleagues find that a specific brain tumor type resembles GABAergic interneuron development, and with this knowledge they identify novel targets against this lethal tumor.
Breeding for Skull Shape Changes the Dog Brain
Sophie Barton shares new research investigating how humans may have unwittingly altered the brain morphology of domestic dogs through selective breeding for head shape. Dogs with extreme head shapes show widespread reductions in gray matter volume across the brain.
Sophie Barton shares new research investigating how humans may have unwittingly altered the brain morphology of domestic dogs through selective breeding for head shape. Dogs with extreme head shapes show widespread reductions in gray matter volume across the brain.
Upcoming Events
Neural Development Club
February 18, 2025
5:30 pm to 7:00 pm
Location: Warren Alpert 236
Featuring talks by: Becky Andersen (Walsh Lab, BCH/HMS) and Yi-Chia Huang (Goodrich Lab, HMS)5:30 pm to 7:00 pm
Location: Warren Alpert 236
gNeuro Special Seminar
March 6, 2025
4:00 pm to 6:30 pm
Location: Cannon Room
Featuring Nick Spencer (Flinders University)4:00 pm to 6:30 pm
Location: Cannon Room