HMS News article on new research from Kun-Hsing Yu and colleagues, co-first authors MacLean P. Nasrallah (Penn) and Junhan Zhao, creating an AI tool that can rapidly decode a brain tumor’s DNA to determine its molecular identity during surgery — critical information can take a few days and up to a few weeks with current approaches.

HMS News article on new research from Khalid Shah and colleagues, first author Kok-Siong Chen, on the development of a new cell therapy approach engineered to eliminate established tumors and to train the immune system to prevent cancer recurrence.

Boston Children's Hospital Answers article on new research from Maria Lehtninen, Naama Kanarek, and colleagues, first author Ahram Jang, on the feasibility of targeting the cerebrospinal fluid and choroid plexus to treat "chemo-brain"-- a side effect of chemotherapy that makes it harder to remember things, maintain attention, and learn new information.

HMS News article on new research from Bob S. Carter, Leonora Balaj, and colleagues, first author Syeda Maheen Batool, describing improvements in a blood test for gene mutations linked to gliomas, the most common type of adult brain tumors. The test previously focused on mutations in the TERT gene, and now has added capability to detect mutations in the EGFR gene.

HMS News article on new research from Kira Bona, Puja J. Umaretiya, and colleagues, showing that race, ethnicity, and poverty are linked to worse outcomes in children treated for high-risk neuroblastomas.

Boston Children's Hospital Answers article on new research from Edward Smith and colleagues, first author Julie Sesen, showing that the levels of a specific protein detected through a patient’s urine can track a tumor’s size and responsiveness to treatment in children with diffuse intrinsic pontine gliomas (DIPG).

Harvard Gazette article on new research from Rakesh K. Jain and colleagues, co-first authors Zohreh Amoozgar, Jonas Kloepper, and Jun Ren, retraining tumor-promoting immune cells to fight most aggressive type of brain cancer.

Missteps during brain development can later lead to the onset of neurologic conditions including brain cancers. Paper highlight by Ryann Fame, Morgan Shannon, Maria Lehtinen.