Neuro Topics - Pain
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photo of clifford woolf
October 10, 2024
Clifford Woolf shares a perspectives piece about what scientists can learn from the opioid crisis as they develop new pain treatments. The piece is part of a special Nature Outlook edition on pain.
Pain-sensing neurons are stained green and red to show activity under a microscope. Image: Tao Deng/NCATS Stem Cell Translation Laboratory/NIH
June 11, 2024
Using mouse and computer model experiments, researchers identified thousands of molecular interactions — most not previously known — between pain-initiating neurons, or nociceptors, and different types of immune cells. These interactions could help explain why pain hypersensitivity sometimes occurs during inflammation — and could also help researchers resolve it.
Original article in: Nature Immunology >
a person suffering from back pain holding their back.
December 7, 2023
Researchers have identified at least one potential link that locks sleep deprivation and chronic pain in an endless loop. Featured in the Harvard Gazette. From Shiqian Shen and colleagues, co-first authors Weihua Ding and Liuyue Yang.
Original article in: Nature Communications >
HMS researchers have identified the molecular conversation that occurs between pain neurons (red) in the gut and intestinal goblet cells (green) as a mechanism involved in protective pain signaling that shields the gut from damage. Image: Chiu Lab/HMS
November 28, 2022
HMS News article on new research from Isaac Chiu and colleagues, first author Daping Yang, illuminating how pain neurons shield the gut from damage.
Original article in: Cell >
magnifying glass over the word anthrax
January 21, 2022
HMS News article on new research from Isaac Chiu and colleagues, first author Nicole Yang, suggesting that anthrax has an unexpected benefit— one specific type of anthrax toxin can silence multiple types of pain in animals.
Original article in: Nature Neuroscience >
A close up of a hand applying an acupuncture needle.
November 12, 2021
HMS News article on new research from Qiufu Ma and colleagues, co-first authors Shenbin Liu and Zhifu Wang, elucidating the underlying neuroanatomy of acupuncture that activates a specific signaling pathway.
Original article in: Nature >
Visualizing_pain
July 29, 2021
HMS News article on new research from Clas Linnman and colleagues, on the development of a new imaging technique allowing researchers to capture images of injuries caused by whiplash that previously eluded scans.
Original article in: Pain >
a woman experiencing tooth pain after eating something cold
May 4, 2021
HMS News article on new research from Jochen Lennerz and colleagues uncovering the molecular and cellular mechanisms behind cold-induced tooth pain and hypersensitivity.
Original article in: Science Advances >
cartoon illustrating touch and pain pathways in a mouse
November 13, 2020
Seungwon (Sebastian) Choi shares new research from the labs of David Ginty and colleagues at the University of Pittsburgh. They applied new mouse genetic tools in conjunction with anatomical, physiological and behavioral approaches to better understand the functional organization of ascending touch, thermal and pain pathways.
Original article in: Nature >
A close up of a hand applying an acupuncture needle.
September 2, 2020
Shen-Bin Liu shares new research from the lab of Qiufu Ma and colleagues on the neurobiology of acupuncture, suggesting it may help treat fatal systemic inflammation in patients with severe infections or for those receiving immune therapy.
Original article in: Neuron >
Josh Sanes
December 20, 2018
Along with along with Larry Zipursky, Josh Sanes has been awarded the 2018 Perl-UNC Neuroscience Prize for the “discovery of cell-surface proteins that control circuit assembly in the visual system.”
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December 20, 2018
Isaac Chiu and Debora Marks were awarded Ben Barres Early Career Acceleration Awards. David Walt and George Church were awarded a Collaborative Science Award by the Chan Zuckerberg Initiative.
Qiufu Ma
December 20, 2018
HMS News article on new research from the lab of Qiufu Ma identifying the nerve pathway that drives sustained pain following injury.
Original article in: Nature >
Paola Arlotta in her lab
December 11, 2018
In the glimpse of the past provided by organoids, Paola Arlotta sees a chance to shape the future of how we fight neurological disease
December 3, 2018
Congratulations to Carl Nist-Lund, Bifeng Pan, Jeffrey Abbott, Tianyang Ye, Swathi Ayloo, Brian Wai Chow, and Kevin Sitek. Each winner will receive $200 and a customized desk plaque with their image.
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December 1, 2018
HMS News article on new research from the labs of Beth Stevens and Steven McCarroll on identifying which microglia in the brain are "good" and which are "bad".
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November 21, 2018
They were recognized for scientifically and socially distinguished work
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November 5, 2018
HMS News article on an announcement by the Bertarelli Foundation and HMS of four new collaborative research grants given to Harvard neuroscientists tackling sensory disorders--from hearing loss, deafness and blindness to acute and chronic pain.
Woolf S1 neurons 850
September 12, 2018
HMS News article highlighting a new study from the labs of Zhigang He, Clifford Woolf and colleagues identifying neurons in the brain that influence touch sensitivity.
Original article in: Nature >