Community Stories

Shown in yellow is a biocytin filled parvalbumin interneuron in the hippocampus of an adult mouse (CA3/CA2 region). The red cells are other parvalbumin interneurons.
August 25, 2026
Amar Sahay shares his lab’s discovery that many ultra-high confidence risk genes for autism, bipolar disorder, schizophrenia, and epilepsy may be regulators of experience-dependent plasticity of inhibitory neurons in the hippocampus of adult mice. Proof-of-concept experiments reveal that targeting one of these regulators can improve cognition and suppress seizures in a common mouse model of neurodevelopmental disorder risk.
Original article in: Nature >
Starburst model showcasing 13 competency areas
February 24, 2026
How do we prepare early-career scientists for today’s wide range of paths in and beyond the lab? Jelena Patrnogić shares a new flexible competency framework she developed with Xiuqi Li and David Van Vactor that makes expectations clearer for trainees, mentors, and programs, and supports growth across both research and professional skills.
Original article in: PLoS Biology >
Human iPSC-derived sensory neurons (green) matured in contact with rodent satellite glia (magenta) develop mature, T-shaped, pseudounipolar morphology. All cell nuclei are shown in blue.
February 3, 2026
iPSC-derived sensory neurons provide an accessible platform for scientists to study sensory biology and disease; however, these cells are similar to embryonic neurons. Chelsey Derderian-LeBlang and Rosalind Segal present a protocol to accelerate the maturation of iPSC-derived sensory neurons, by providing external signals from satellite glial cells. They show that satellite glia, while previously described as a support cell, play a major role in both sensory neuron development and degeneration.
Original article in: Stem Cell Reports >
Novel environment exploration turns on new gene expression in the hippocampus, controlled in part by the activity-dependent transcription factor FOS, a well-known gene that rapidly responds to novel sensory experiences. Representative immunofluorescence image of FOS (magenta) protein levels in the CA1 region of the hippocampus from home cage (HC) and 90 min following a 30 min novel environment (NE) exposure. Gray indicates DAPI-stained nuclei.
January 14, 2026
New experiences trigger rapid changes in gene activity and DNA accessibility in the brain’s memory-center, the hippocampus. Lisa Traunmüller and Erin Duffy describe new research from the Greenberg lab that uses advanced sequencing to map how different hippocampal regions respond at the molecular level to a novel environment — revealing how experiences shape brain circuits that underlie learning and memory.
Original article in: Nature Communications >

In the News

a closeup of a us military member saluting
August 25, 2026
Male veterans of the U.S. Air Force, Navy, and Coast Guard had higher rates of amyotrophic lateral sclerosis (ALS), a fatal nervous system disease, compared to veterans of the Army, according to a new study from Marc G. Weisskopf, Andrea Roberts, and colleagues.
Original article in: Neurology >
Artist rendition of brain circuitry. Image: nopparit/E+/Getty Images
August 25, 2026
For decades, neuroscientists have been able to record which parts of the brain show increased electrical activity during a behavior, such as when we form a memory or make a decision. But scientists haven’t been able to determine how those regions are communicating with and influencing one another, nor identify which regions serve as the main orchestrators. A new artificial intelligence framework called Current-Based Decomposition, or CURBD, can now make that distinction.
Original article in: Neuron >
orepinephrine-producing axons (stained green) and dopamine-producing cells (stained magenta) can be intermixed in the brain. Image: Ricardo López
August 25, 2026
A lot is known about communication via classically described synapses, but over the last decade, new tools have allowed scientists to focus increasingly on other, more diffuse systems, in which brain chemicals called neuromodulators communicate with many different cells over longer time frames. New research shows that fluorescent sensors commonly used in this research can mix up two neuromodulators: dopamine and norepinephrine. 
Original article in: Nature Neuroscience >

Awards & Honors

blue award ribbon illustration
August 5, 2026
Round up of awards and honors earned by the HBI community.
blue award ribbon illustration
July 13, 2026
Round up of awards and honors earned by the HBI community.