Yuqin Yin and Larry Benowitz describe a new study using RNA sequencing and bioinformatics to identify the transcription factor REST (a.k.a. NRSF) as a key repressor of the genetic program required for neurons to regenerate axons in the central nervous system. Counteracting the inhibitory effects of REST enhances the ability of retinal ganglion cells to regenerate axons through the injured optic nerve and of cortical neurons to regenerate axons in the corticospinal tract.

Harvard Gazette article on research probing the molecular basis for the stinging response in sea anemones and jellyfish, and identifying how these organisms detect and filter cues from the environment when making the decision to sting or not sting. From the labs of Nicholas Bellono, Amy Lee and colleagues, first author Keiko Weir. 

A new study from Keiko Weir and colleagues in lab of Nicholas Bellono, addresses the question of how single nematocytes detect and filter diverse cues from their environment to control when (and when not) to sting.