Neuro Topics - Circadian Rhythm
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August 6, 2024
Susan Dymecki and colleagues (First author Giacomo Maddaloni) have identified a mouse brain circuit with multiple groups of neurons that together recognize, decode, and drive behavioral adaptation to changes in the amount of daylight.
Original article in: Nature >
August 6, 2024
Joe Kossowsky and colleagues (first author Danielle A Wallace) found that participants who spent more time in bright light had more regular sleep, and that more regular sleep was associated with lower depression symptoms and lower odds of mild or severe depression
Original article in: JAMA Network Open >
February 2, 2024
Researchers from Mass. General Hospital, University College London, and the University of the Republic in Uruguay found a two-way association between anorexia-related genes and those associated with the morning chronotype (waking early/going to bed early). This contrasts with disorders such as depression, binge eating disorder, and schizophrenia, which are associated with an evening chronotype.
Original article in: JAMA Network Open >
October 26, 2023
The time of day influences cognition, but the molecular and synaptic mechanisms of this influence are elusive. We show that the circadian clock protein BMAL1 has a rhythm in synapses that is critical for corresponding rhythms in synaptic plasticity. Our findings point to local mechanisms for gating computations in anticipation of the time of day.
Original article in: Science Advances >