Neuro Topics - Blood-brain barrier
SEARCH OTHER RESEARCH AREAS
When researchers injected fluorescent dye (blue) into the circulatory system of a zebrafish with a spock1 mutation, the dye leaked out of blood vessels (pink) in the forebrain and midbrain (left), but stayed relatively confined within the hindbrain (right), revealing a blood-brain barrier that was permeable in some areas but not others. Image: Natasha O’Brown
July 21, 2023
HMS News article on new research from Sean Megason, Chenghua Gu, Allon M. Klein, and colleagues, first author Natasha O'Brown, using mice and zebrafish to discover a signal produced by neurons that helps the blood-brain barrier form and maintain its protective properties.
Original article in: Developmental Cell >
Illustration of skull with brain showing
May 24, 2022
Harvard Gazette article on new research from Matthias Nahrendorf and colleagues, co-first authors Fadi E. Pulous and Jean C. Cruz-Hernández, finding that cerebrospinal fluid (also known as “brain water”) can exit the brain into the skull’s bone marrow through tiny channels in the skull, and this may be key to detecting infection and injury.
Original article in: Nature Neuroscience >
normal blood vessels in the retina
April 21, 2022
HMS News article on new research from the lab of Chenghua Gu, first author Swathi Ayloo, identifying a new mechanism regulating the permeability of the blood-brain barrier in mice.
Original article in: Neuron >
CZI Thumbnail
June 21, 2019
The Chan Zuckerberg Initiative (CZI) recently selected 38 collaborative science teams to launch CZI’s Seed Networks for a Human Cell Atlas projects, including a Harvard team focused on mapping cells of the human eye from birth to old age.
Wyss_Institute
June 21, 2019
Wyss Institute scientists have developed chip technology that mimics the blood-brain barrier in humans. The new models will help researchers study drugs to treat cancer, neurodegeneration, and other diseases of the central nervous system.
Original article in: Nature Communications >
Chenjezo_Gonani
May 20, 2019
Chenjezo Grant Gonani wants to build culturally relevant mental health care
retinal-microglia-850 (https://hms.harvard.edu/sites/default/files/media/retinal-microglia-850.jpg)
April 30, 2019
HMS News article highlighting new research from the lab of Kip Connor (first author Yoko Okunuki), on how unraveling microglia’s role in neuroinflammation could improve treatment for visual disorders like uveitis.
Original article in: PNAS >
cannabis
April 30, 2019
Harvard Medical School receives $4.5 million for cannabinoid research from Harvard University from Charles R. Broderick, an alumnus of Harvard University and MIT.
Brain Blood
September 21, 2018
Harvard Gazette article on new organ on a chip that lets researchers study effects of drugs and disease on the brain and the importance of blood vessels. From the labs of Donald E. Ingber, Kevin Kit Parker and colleagues.
Original article in: Nature Biotechnology >