Nature Over Nurture: Functional Neuronal Circuits Emerge in the Absence of Developmental Activity
From the lab of Florian Engert. Co-first authors Dániel Barabási and Gregor Schuhknecht. Featured in MCB News.
The Engert lab found that in zebrafish, previous visual experience had no effect on the emergence of their optomotor response (OMR). Fish raised in the dark (no visual experience) and fish raised under a strobe light (irregular visual experience) both developed this visually-guided behavior normally. Brain-wide imaging suggested that relevant neuronal circuits came ‘online’ fully tuned, without a need for activity-dependent plasticity.
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