New research uncovers how inflammation damages excitatory synapses in an experimental model of MS. While there is a constant turnover of synapses in the healthy brain, inflammation accelerates this turnover so that synapses were gained and lost at higher rates. This widespread instability impacts the entire neuron and leading to important changes in the incoming inputs to individual neurons.

From the team of Brian J. Bacskai and colleagues, first author Rebecca Gillani. Read more at the the Mass. General Hospital Newsroom.