Our third symposium celebrating cross-campus collaborations in neuroscience at Harvard, hosted by Dragana Rogulja

1:30 Coffee & Registration  |  2:00 to 5:00 Talks  |  5:00 to 6:00 Poster Session

2:00 to 3:30 Highlights from HBI’s
2018-2019 Collaborative Seed Grant Awardees

Joshua Kaplan, presenting collaboration with Yun Zhang
“Food or foe: C. elegans detection of a bacterial pathogen”

Margaret Livingstone, presenting collaboration with Talia Konkle
“Tuning all the way down”

Wade Harper, presenting collaboration with Lee Rubin
“Cullin-RING ligase dynamics during changes in cell states”

L. Mahadevan, presenting collaboration with Maxwell Heiman
“Topological and geometrical organization of neuronal bundles”

4:00 to 5:00 Keynote Lecture
Elizabeth Phelps, “Mechanisms of Threat Control”

5:00 to 6:00 Posters & Reception
Featuring the work of students, fellows and lab staff in neuro labs from all parts of the University and affiliated hospitals. Presenters and poster titles listed below:

VAST Lite, a tool for efficient manual and semi-automatic labeling of large 3D image stacks
Berger DR, Seung HS, Lichtman JW
Presented by Daniel Berger, PhD

Hierarchical motion structure is employed by humans during visual perception.
Bill J, Pailian H, Gershman SJ, and Drugowitsch J.
Presented by Johannes Bill, PhD

The antennal lobe is a Drosophila melanogaster locus of behavioral individuality
Churgin M, de Bivort B
Presented by Matthew Churgin, PhD

Motor Preparatory Signals Activate Auditory Corticothalamic Neurons
Clayton KK, Williamson RS,  Tasaka G, Mizrahi A, Hackett TA,  Polley DB
Presented by Kameron Clayton

Structural features supporting synchronization of SCN core neurons
Czeisler ME, Shan Y, Berger DR, Schalek RL, Peleg A, Takahashi JS, Lichtman JW
Presented by Mark Czeisler

A molecular approach to treat cognition in schizophrenia by calcium channel blockade: An open-label pilot study of the calcium-channel antagonist isradipine
Harper C, Perez-Rodriguez M, Birnbaum R, Shanahan M, Larsen E, Sklar P, Burdick KE
Presented by Cierra Harper

Studying clonal distributions and cell lineage in adult human brain using somatic mutations
Kim SN, Doan RN, Barton AR, Dou Y, Tsai JW, Lodato MA, Lee S, Park PJ, Walsh CA
Presented by Sonia Nan Kim

A potential role of IGF-1 and APOE in regulating stress-induced autophagy in late-onset Alzheimer’s disease
Liao W, Bormann M, Ryu WI, Healy RA, Shen M, Cohen BM, Sonntag KC
Presented by ‘Leo’ Wang Liao

Molecular and Cellular Mechanisms for Establishing Neuronal Connectivity
May E, Nicoludis J, Chiang B, Dang N, Gaudet R
Presented by Elizabeth May

Identification of genetic modifiers of somatic CAG repeat instability by in vivo CRISPR-Cas9 genome editing
Azevedo A, Murtha R, Kovalenko M, Andrew M, Zhang F, Lee J, Wheeler V, Mouro Pinto R
Presented by Ricardo Mouro Pinto, PhD

Learning of pathogenic bacteria in adult C. elegans bidirectionally regulates pathogen 1 response in the progeny
Pereira AG, Gracida X, Kagias K and Zhang, Y
Presented by Ana Pereira, PhD

Profiling bioenergetics in iPSC-derived neural precursor cells and astrocytes from Alzheimer’s disease patients and non-demented control individuals
Ryu WI, Healy RA, Bormann MK
Presented by Wooing Ryu, PhD

An in-vitro model for blood-brain barrier (BBB) on chip to enable imaging therapeutic antibody trancytosis using lattice light-sheet microscopy (LLSM) with high spatial and temporal resolution
Salman M, Marsh G, Küsters I, Upadhyayula S, de Nola G, Hunt R, Obermeier B, Kleiman R, Kirchhausen T
Presented by Mootaz Salman, PhD

Distinct symptom-specific targets for circuit-based neuromodulation
Siddiqi SH, Taylor SF, Cooke DC, Pascual-Leone A, George MS, Fox MD.
Presented by Shan Siddiqi, PhD

Proteomic and phosphoproteomic changes during normal and drug-promoted differentiation of human neural progenitor cells
Song Y, Subramanian K, Berberich MJ, Rodriguez S, Latorre IJ, Luria CM, Everley R, Albers MW, Mitchison TJ, Sorger PK.
Presented by Yuyu Song, PhD

Feed-forward inhibition, ensemble dynamics and remote memory
Twarkowski H, Steininger V, Sahay A
Presented by Hannah Twarkowski, PhD and Victor Steininger

Mesoscopic functional interactions in the human cortex
Wang J, Anderson WS, Madsen JR, Kreiman G
Presented by Jerry Wang

Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes
Presented by Qingbo Wang

A computational model of hybrid visual search
Wick FA, Kreiman G, Wolfe JM
Presented by Farahnaz A. Wick, PhD