The Sinclair lab is driven by the belief that humanity can do better and that everyone has the right to the best medical care and maximum lifespan, no matter their gender, social status, or age. Work by our lab and others has shown that the pace of aging is not inexorable or predetermined, but rather can be slowed and even reversed by a variety of approaches. These include activating the body’s defenses against aging, deleting senescent cells, and reprogramming cells in vivo. In doing so, we can protect the body against and treat both rare and common diseases including mitochondrial diseases, type 2 diabetes, Alzheimer’s disease, cardiovascular disease, and cancer.